Toward Establishing a Therapeutic Window for rTMS by Theta Burst Stimulation
نویسنده
چکیده
In this issue of Neuron, Huang et al. show that a version of the classic theta burst stimulation protocol used to induce LTP/LTD in brain slices can be adapted to a transcranial magnetic stimulation (TMS) protocol to rapidly produce long lasting (up to an hour), reversible effects on motor cortex physiology and behavior. These results may have important implications for the development of clinical applications of rTMS in the treatment of depression, epilepsy, Parkinson's, and other diseases.
منابع مشابه
Theta, alpha and beta burst transcranial magnetic stimulation: brain modulation in tinnitus
INTRODUCTION Some forms of tinnitus are considered to be auditory phantom phenomena related to reorganization and hyperactivity of the auditory central nervous system. Repetitive transcranial magnetic stimulation (rTMS) is a non-invasive tool capable of modulating human brain activity, using single pulse or burst stimuli. Burst rTMS has only been performed in the theta range, and has not been u...
متن کاملRepetitive TMS over the human oculomotor cortex: comparison of 1-Hz and theta burst stimulation.
The aim of the study was to compare the effect duration of two different protocols of repetitive transcranial magnetic stimulation (rTMS) on saccade triggering. In four experiments, two regions (right frontal eye field (FEF) and vertex) were stimulated using a 1-Hz and a theta burst protocol (three 30Hz pulses repeated at intervals of 100ms). The same number of TMS pulses (600 pulses) was appli...
متن کاملRepetitive transcranial magnetic stimulation in delirium: A double-blind, randomized, sham-controlled, pilot study
Purpose: Delirium is a fatal but potentially reversible disorder of Central Nervous System that adds a lot of costs on health systems. The aim of this study was to evaluate the effect of intermittent theta burst stimulation on severity and course of delirium. Methods: This was a double-blind, randomized, sham-controlled, pilot study. The participants were randomly allocated into two groups of ...
متن کاملEffectiveness of theta-burst repetitive transcranial magnetic stimulation for treating chronic tinnitus.
OBJECTIVES Repetitive transcranial magnetic stimulation (rTMS), a noninvasive method for altering cortical excitability, is becoming a therapeutic strategy in auditory research institutions worldwide. Application of inhibiting rTMS on these overactive cortical regions can result in effective tinnitus suppression. The aim of this study is to investigate the efficacy of theta-burst rTMS in patien...
متن کاملTheta Burst Stimulation of Human Cortex
It has proved possible in experimental animals to manipulate synaptic efficiency using direct electrical stimulation of central nervous pathways. The introduction of transcranial methods of non-invasively stimulating the human brain raised hopes that similar effects could be produced in humans, with the potential for eventual therapeutic application in disease states. However, largely due to sa...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Neuron
دوره 45 شماره
صفحات -
تاریخ انتشار 2005